Past Grants and Projects

2014 to present: All grants are co-funded by national Ring14 chapters through Ring14 International.

2011 – 2014: Grants jointly between Ring14 Italy and Ring14 USA.

Prior to 2011: Grants were funded through Ring14 Italy.

scientist in laboratory

AN INFANTILE RAT MODEL OF EPILEPSY FOR TESTING NOVEL DISEASEMODIFYING DRUGS FOR RING14 SYNDROME

Project LeaderVezzani Annamaria
Host InstitutionIRCCS-Mario Negri Institute for Pharmacological Research, Milan (Italy)
Duration1 year
Start-up dateJanuary 2017
Financed amount€ 50.000
StatusCompleted

ANALYSIS OF RING14 CHROMOSOME IN HUMAN NEURONAL TISSUES

Project LeaderSpinner Nancy B.
Host InstitutionUniversity of Pennsylvania, Philadelphia (USA)
Duration1 year
Start-up dateNovember 2015
Financed amount€ 50.000
StatusCompleted

PRODUCTION OF STABLE AND INDUCIBLE (IPSC) CELL MODELS OF THE RING14 SYNDROME

Project LeaderWynshaw-Boris Anthony
Host IntitutionCase Western Reserve University, Cleveland (USA)
Duration1 year
Start-up dateNovember 2015
Financed amount€ 50.000
StatusCompleted

RING 14 SYNDROME: TOWARDS A DETAILED CORRELATION BETWEEN GENOTYPE AND PHENOTYPE

Project LeaderOrsetta Zuffardi
Host InstitutionInstitute of Medical Genetics, University of Pavia (Italy)
Duration2 years
Start-up dateOctober 2013
BudgetThe project is entirely funded by Telethon (www.telethon.it)
StatusCompleted

GENE EXPRESSION ANALYSIS IN RING CHROMOSOME 14 SYNDROME

Project LeaderNancy Spinner
Host InstituteThe Children’s Hospital of Philadelphia at The Perelman School of Medicine at the University of Pennsylvania USA
Duration2 years
Start-up dateOctober 2012
Amount financed€ 116.000
StatusRenewed project

GENERATION OF THE RING14 MOUSE MODEL TO BETTER UNDERSTAND THE PATHOPHYSIOLOGY OF THE HUMAN SYNDROME

Project LeaderYann Herault
Host InstitutionDirector of Institute Clinique de la Souris, Institute of Genetic and Molecular and Cellular Biologic IGBMC, INSERM U964, CNRS, University of Strasbourg
Duration2 years
Star-up dateAugust 2012
Financed amount€ 93.000 (co-financed by 50% from Ring14)
StatusCompleted

LANGUAGE DEVELOPMENT IN CHILDREN SUFFERING FROM CHROMOSOME 14 SYNDROMES

Project LeaderLaura Zampini
Host InstitutionDept. of Psychology, Bicocca University, Milan (Italy)
Duration8 years
Start-up year2007
Budget€ 50.000 (wholly financed by Ring14 Italy)
StatusCompleted

PROJECT ON THE GENETIC BASIS OF THE RING14 SYNDROME

Project LeaderGiovanni Neri
Host InstitutionIstituto di Genetica Medica, Università Cattolica di Roma (Italy)
Duration8 years
Start-up year2004
Budget€ 171.200
StatusCompleted